IHE tracks a broad index of US pharmaceutical companies. The fund provides exposure to the manufacturers of prescription or over-the-counter drugs, such as aspirin, cold remedies and birth control pills. The index also includes vaccine producers. IHE may also include companies of all sizes, ranging from large- to small-cap. The index weights its constituents by market cap, with a cap of up to 22.5% per individual company and is rebalanced quarterly. IHE uses a sampling strategy that involves investing in a representative sample of securities that collectively has an investment profile similar to that of an applicable underlying index. Index components are selected on an annual basis.